EML4501 Capstone senior Design Presentations:
August 2nd and August 4th, specific times noted in each group
Functional imaging is an advanced biomedical technique to probe physiological activity in living tissues by visualizing spatial-temporal distribution of chemical-physical tracers within an organism. In humans, for example, functional magnetic resonance imaging (MRI) detects brain injuries otherwise invisible to conventional structural imaging techniques. Our customer, UF’s Integrative Mechanobiology Lab, seeks EML4501 mechanical engineers to design a new biomedical product: a high-throughput Selective Plane Illumination Microscopy (SPIM) functional imaging system for in-vivo studies. A working prototype of this system exists at UF in NEB 148, and our goal is to draw insight from this prototype to develop a commercial Zebrafish SPIM Functional Imager capable of being used reliably and reputably by a lab technician for deployment by companies and research labs. Ultimate applications include measuring relationships between neuron activity and animal behavior to understand the electrochemical function of new therapies and drugs. Early adopters of this product include microscope companies who will market the SPIM as an add-on to their platforms as well as drug companies and research institutions that conduct therapy and drug discovery research and development. 00 °C, while eliminating shading effects, achieving high optical efficiencies, and decreasing overall cost below $100 per square meter. Further detail on the design expectations and 18 required design metrics can be found in the Summer 2022 EML4501 Customer Needs Statement.
For external feedback providers, click here to access the evaluation survey.
Click below to view each team’s abstract, 90-second pitch, and to access their Zoom meetings:
Group 1 – ZOS SPIM – Ashley Booth, Alex Lugo, Alexis Hernandez, Natasha Polito, Spencer Schmidt, Michael Seaman, Gavin St John
Group 2 – AQUARIUM DISRUPTERS – Lyle Hayes-Macaluso, Andrew Michael, Matthew Zammataro, Kaio Bui, Gavin Drawdy, Anton Nguyen, Jackie Le
Group 4 – ZEBRAFISH SPIM SYSTEM – James Acosta, Crae Andrew, Elan Gavish, Dante Macean, Jeffrey Morris, Xinyu Wang, Patricio Miranda
Group 5 – ZEBRAFISH HATERZ – Augusto Munoz, Augustus Heal, Bryan Mejia, Chase Manning, Heyang Wang, Rachel Lucas, Xin Hai
Group 6 – ZEBRA-TEAM 6 – Hugh Brittenham, Alexander Davis, Alexander Hadid, Eric Lee, Cyril Moran, Ami Patel, Brett Winter